Medical Gene Technology Unit

Leader: Gábor Szabó


The Medical Gene Technology Unit (MGTU) is a professionally independent, financially self-managed research animal facility of the institute conducting animal- and gene technology service, research & development activity.

MGTU comprises a high-capacity "SPF-specified pathogen free” research animal facility suitable for housing and breeding genetically modified mice (GM) mostly in individually ventilated cage-system and a "nearly-pathogen free" (MD-minimal disease) animal facility mostly used by the researchers; a conventional receiving quarantine station and a gene technology unit. The latter consists of a microinjection laboratory behind the SPF barrier, genotyping and molecular biology laboratories.

MGTU’s diverse professional activity covers almost the full spectrum of animal gene technology.

It includes the export/import of genetically modified (GM) mice; rederivation of GM mouse lines by embryo transfer and in vitro fertilization (IVF) to eliminate potential pathogens; repopulation of full animal facilities by rederivation; the establishment, maintenance, breeding and genetic crossing of GM colonies for the production of complex mouse models; archiving GM lines as frozen embryos and sperm; DNA-based genotyping. The Unit’s high priority activity is to produce genetically engineered mouse models using microinjection technology including DNA fragment-, modified BAC-, transposase- and CRISPR/Cas9 based techniques.

MGTU provides a full spectrum of animal- and gene technology service to the entire research community supporting academic basic research as well as applied research and development of the pharmaceutical industry.

This continuously improved high value technology portfolio is not available elsewhere in the country.


Excerpt from the Guidebook of the Institute 2015.

Members:

NévBeosztás
Katalin BartosekAnimal-technician
Balázs BecseyCaretaker of MGTU
Ágnes DobosGenet Technologist
Ferenc ErdélyiAssociated Research Fellow, Manager of Unit
Zsuzsanna ErdélyiGene Technologist
Geszlerné Mária EcsédiAnimal-technician
Józsefné HajduAnimal-technician
Zója KatarovaSenior Research Fellow
Kaziné Mária Szücs Animal Caretaker
Zita KisLaboratory Technician
Katalin KovácsEmbryologist/Injectionist
Pálma KunAnimal Caretaker
Zoltán MátéPhD Student
Adrienn MáthéAnimal Caretaker
Miklós MénessyAnimal Caretaker
Alexa NagyAnimal-technician
Gábor SzabóSenior Research Fellow, Head of Unit
Miklós TóthaAnimal Caretaker
Ujjobbágyné Tünde J.Animal Caretaker